Tuberculosis due to asbestos exposure

Often, misdiagnosis or diagnostic delays happen because tuberculosis mimics the clinical as well as radiological features of most interstitial lung diseases caused by prolonged exposure to dangerous materials, including asbestos. Pleural effusion is a common manifestation of tuberculosis and asbestos-related pleural disease, which is why a pleural biopsy is essential to rule out tuberculosis in patients with suspected asbestos-related pleural effusion.

With a tuberculosis diagnosis alone, you are not eligible for compensation. But given the fact that the rate of misdiagnosis is high, and the cancer risk is high with asbestos exposure, we strongly recommend you get a second and even third opinion outside the VA. If you are diagnosed with asbestos-related cancer, you become eligible to file a claim and obtain financial compensation.

Tuberculosis is the 7th leading cause of death worldwide

According to the CDC, 9,105 cases of tuberculosis were diagnosed in the United States in the year 2017. The prevalence of pulmonary tuberculosis being diagnosed along with asbestosis ranges from 3.8%-36%, thus establishing an association between the two lung disorders. Patients with asbestosis show poor immune response and reduced defensive capacity of the lung, which makes them prone to infections, including Mycobacterium tuberculosis.

In 2002, a single-blind cohort study reported an association between asbestos exposure and pulmonary tuberculosis in a group of Iranian factory workers, which included 202 workers exposed to asbestos and 201 workers non-exposed to asbestos. The study concluded that exposure to asbestos is a predisposing factor to the development of secondary tuberculosis, which may occur due to the reactivation of dormant foci of Mycobacterium infection in the lungs. According to the American Lung Association, more than 9.6 million people suffer from an active form of tuberculosis. People with a latent form of tuberculosis are asymptomatic and carry a 15% lifetime risk of developing an active infection; the risk is higher in immunocompromised individuals.

Common signs and symptoms of tuberculosis and interstitial lung diseases

The signs and symptoms of asbestosis and other interstitial lung diseases are quite similar to the symptoms of other lung diseases, including tuberculosis. The table below summarizes and compares the symptoms of tuberculosis and asbestos-related interstitial lung disease:

Tuberculosis

Interstitial Lung Diseases
(Asbestosis)

  • Difficulty in breathing
  • A persistent cough, productive
  • Weight loss
  • Fever
  • Fatigue
  • Chest pain
  • Shortness of breath
  • Dry, non-productive cough
  • Weight loss
  • Increased fatigue on exertion
  • Fever
  • Chest pain
  • Clubbing of fingers

Generally, the most common symptoms of a respiratory disorder, such as a cough and difficulty breathing, tend to get overlooked or sometimes wrongly attributed to habits such as smoking, aging, or infections, more commonly tuberculosis. This can lead to patients being subjected to unnecessary anti-tuberculous treatment and its side effects, as well as a delay in receiving appropriate care. Therefore, early diagnoses of interstitial lung diseases, including asbestosis, require a higher degree of clinical suspicion.